Posted on 18 November 2010. Tags: catheter, central canal stenosis, cervical radiculopathy, David Fish, depo-medrol, disc, disk herniation, epidural steroid injection, ESI, interlaminar, magnetic, Methylprednisolone, MRI, NDI, neck disability index, neuroforaminal stenosis, radiculopathy, UCLA
By Chris Faubel, MD –

Image courtesy Dr. Hazem Eissa
Am J Phys Med Rehabil. 2009 Mar;88(3):239-46
MRI prediction of therapeutic response to epidural steroid injection in patients with cervical radiculopathy.
Fish DE, Kobayashi HW, Chang TL, Pham Q.Department of Orthopaedics, Physical Medicine and Rehabilitation, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Get the abstract here
Summary of Study
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- Purpose: to find out if particular MRI finding can predict therapeutic success from cervical interlaminar epidural steroid injections (C-ILESIs) in patients with cervical radiculopathy
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Posted in Cervical Epidurals, Cervical Spine, Journal Club
Posted on 11 November 2010. Tags: asymptomatic, Boden, bulge, cervical spine, cord, degeneration, disc, false positive, foraminal stenosis, herniation, magnetic resonance imaging, MRI, neuroradiologists, pathology, prospective
By Chris Faubel, MD –

Source: The Journal of Bone and Joint Surgery. This is a 34 year old asymptomatic woman. Note the disc herniation contacting the cord between the 4th and 5th vertebrae
The Journal of Bone and Joint Surgery. 1990;72:1178-1184
Abnormal magnetic-resonance scans of the cervical spine in asymptomatic subjects. A prospective investigation
SD Boden, PR McCowin, DO Davis, TS Dina, AS Mark and S Wiesel
Department of Orthopaedic Surgery, George Washington University Medical Center, Washington, D.C. 20037
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Summary of Study
- Purpose: to document the prevalence of cervical spine MRI pathology in asymptomatic individuals (false positives)
- Prospective study
- Sixty-three (63) asymptomatic volunteers (20-73 years old)
- Subjects had to have no history of cervical pain or trauma, pain in the shoulder, or radicular symptoms referable to the cervical nerve-roots.
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Posted in Asymptomatic MRI, Cervical Spine, Journal Club
Posted on 12 October 2010. Tags: animal study, decadron, depo-medrol, dexamethasone, Methylprednisolone, non-particulate, particulate, pigs, prednisolone, spinal cord infarction
By Chris Faubel, MD –

Source: Mayo Foundation for Medical Education and Research
J Bone Joint Surg Am. 2008 Sep;90(9):1932-8.
Perils of intravascular methylprednisolone injection into the vertebral artery. An animal study.
Okubadejo GO, Talcott MR, Schmidt RE, Sharma A, Patel AA, Mackey RB, Guarino AH, Moran CJ, Riew KD.
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA. gokubadejo@hotmail.com
Get the abstract here
Summary of Study
- Purpose: to investigate whether use of particulate steroids carried with it, a greater risk of neurologic damage from cervical transforaminal epidural steroid injections
- Prospective, exploratory pilot study
- Animal study – eleven (11) adult, male pigs weighing between 110 and 136 pounds (50-62 kg)
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Posted in Cervical Epidurals, Cervical Spine, Journal Club