Archive | History of Glucocorticoids

Adrenal Glands

The History of Corticosteroids (Glucocorticoids)

By Chris Faubel, MD –

  • The discovery of the class of corticosteroid called glucocorticoids began in the 1920′s.

    Image courtesy A.D.A.M.

  • In the 1920’s, rheumatoid arthritis and other arthritidies were thought to have an infectious cause.
  • By 1938, Dr. Philip Hench from the Mayo rheumatic disease service, noticed a 65yo doctor with arthritis that improved the day after becoming jaundiced.
    • He later noted 31 other cases of joint pain resolving, to some extent, with pregnancy, infections, and post-surgically.
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