The following information is NOT meant to be used to treat yourself or patients.
- Generic name = Meloxicam
- Trade name = Mobic
- Class = anti-inflammatory
- MOA
- Blocks cyclooxygenase (COX-1 & COX-2) and thus production of prostaglandins
- Thought to inhibit COX-2 more than COX-1 (click here for a chart)
- Blocks cyclooxygenase (COX-1 & COX-2) and thus production of prostaglandins
- Advantages
- BID dosing
- Inexpensive: On the Target and Wal-Mart $4/month generic lists
- Dosing
- 7.5, 15-mg tablets
- Note:
- COX-1 normally produces prostaglandins that are gastroprotective. Thus, blocking it can lead to gastric ulcers/bleeds
- Take with food or 8-oz of water
- May increase risk of cardiovascular thrombotic events, MI, and stroke
- Avoid in patients with cardiac history
- Absolute contraindications: ASA allergy, gastritis/ulcer, severe hepatic impairment, CABG
