Anti-inflammatories, Etodolac - Lodine, Medications, Miscellaneous

Etodolac – Lodine

The following information is NOT meant to be used to treat yourself or patients

Generic name= Etodolac

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Trade name = Lodine

Class = anti-inflammatory


  • Blocks cyclooxygenase (COX-1 & COX-2) and thus production of prostaglandins


  • 200, 300, 400, 500, 600-mg pills
  • Typically prescription: 200-400mg TID or QID
  • Max dose: Do not exceed 1200-mg/day


  • COX-1 normally produces prostaglandins that are gastroprotective.  Thus, blocking it can lead to gastric ulcers/bleeds.
  • Take with food or 8-oz of water
  • May increase risk of cardiovascular thrombotic events, MI, and stroke
    • Consider avoiding in patients with cardiac history
  • Absolute contraindication: ASA allergy
  • Use with caution in renal and liver impairment

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