The following information is NOT meant to be used to treat yourself or patients
Generic name = Ibuprofen
Trade name = Advil, Motrin
Class = anti-inflammatory
MOA
- Blocks cyclooxygenase (COX-1 & COX-2) and thus production of prostaglandins
Advantages
- Relatively inexpensive as generic
- Available over-the-counter
Dosing
- 50, 100, 200, 300, 400, 600, 800-mg pills
- Comes in 200-mg pills over-the-counter
- For acute, short-term use, it is typically prescribed as 800-mg four times a day for a week
- Max dose: Do not exceed 800-mg/dose and 3200-mg/day for more than a week
Note:
- COX-1 normally produces prostaglandins that are gastroprotective. Thus, blocking it can lead to gastric ulcers/bleeds.
- Take with food or 8-oz of water
- May increase risk of cardiovascular thrombotic events, MI, and stroke
- Consider avoiding in patients with cardiac history
- Absolute contraindication: ASA allergy
- Use with caution in renal and liver impairment
